The endocannabinoid system is a complex network of proteins, enzymes and receptors which is found in all mammals. It helps regulate many different physiological processes including pain, immune system function, sleep, mood, appetite, and memory. The endocannabinoid system works by producing its own cannabinoids, called endocannabinoids, which bind to and activate receptors throughout the body. CBD (cannabidiol) is a cannabinoid found in hemp plants that has been found to interact with the endocannabinoid system to produce a variety of therapeutic effects.
The CBD pathway is a part of the endocannabinoid system that includes CB1 and CB2 receptors and many other proteins, enzymes, and receptors. There are two major cannabinoid receptors found in the brain of mammals: CB1 is mainly found in the brain while CB2 is mainly found in immune cells. The endocannabinoid system is what mediates marijuana’s medical effects by binding to these two receptors to produce its physiological effects.
CBD has been shown to have therapeutic activities through four different mechanisms of action: 1) via inhibition of fatty acid amide hydrolase (FAAH 2) antagonizing the central CB1 receptor, 3) decreasing ceramide synthesis, and 4) LOR (AOR)-mediated inhibition of histone deacetylases.The endocannabinoid system has a crucial role in regulating inflammation and pain. For example, the activation of CB2 receptors decreases the release of pro-inflammatory cytokines from immune cells and activates certain anti-inflammatory pathways such as IL-4 signaling. As CBD changes the way that endocannabinoids are processed in the brain, it is thought to be able to alleviate anxiety symptoms, stress relief, and affect mood disorders by binding to—— and activating—CB2 receptors.
CBD, or cannabidiol, is a naturally-occurring compound found in the cannabis plant that has been linked to a variety of health benefits. It is non-psychoactive, so it won’t get you high, and it can be used in many ways such as through tinctures, edibles, and topicals. CBD can help with pain relief, anxiety reduction, and improved sleep quality. At cbdgdl.com, you’ll find a wide selection of quality CBD products at competitive prices with fast shipping. By shopping with cbdgdl.com, you can be sure you’re getting the best quality CBD products from a reliable seller.
